High spatial resolution non-contact temperature measurement

Rensselaer researchers have developed a scanning electron microscopy based temperature mapping technique which employs a temperature sensitive electron signal for nano-scale resolution, non-contact measurement. It provides enhanced capabilities for investigating heat generation and transfer at the nanoscale to address long-standing issues related to power consumption, heat dissipation and energy conversion efficiency in many current and future generation nano-engineered systems.

Probe-based High Precision Spatial Orientation Control and Assembly of Parts for Microassembly using Computer Vision

This technology relates to visually-guided multiprobe microassembly for assembling micro-electromechanical (MEMS) devices from multiple parts that are assembled rather than using bulk-processes to produce devices monolithically. Current production technologies primarily use a single wafer that is process chemically to produce finished devices. While this is useful for many devices, it results in mechanical regions that exist primarily in the plane and do not have fully spatial mechanisms without significant depth of stacked parts.


Lookback is defined as the ability of a logical process to change its past locally (i.e. without involving other logical processes). Logical processes with lookback are able to process out-of-timestamp order events, enabling new synchronization protocols for the parallel discrete event simulation. This technology is directed to two of such protocols, LookBack-Global Virtual Time (LB-GVT) and LookBack-Earliest Input Time (LB-EIT), which are presented and their performances on the Closed Queuing Network (CQN) simulation are compared with each other.


Many proteins lose enzymatic activity in harsh environments, such as non-optimal pH or temperature, or exposure to organic solvents. This invention is based on the discovery that by attaching certain proteins to single-walled carbon nanotubes ("SWNT"), protein function under such harsh conditions can be dramatically improved. Two enzymes which were stabilized in this manner, subtilisin carlsberg and soybean peroxidase, were found to be orders of magnitude more active than the native state enzyme when exposed to severe environments. Additionally, the enzymes attached to the SWNTs w

Enzyme immobilization for electroosmotic flow

While there have been rapid advances in microscale device fabrication, microfluidics, and lab-on-a-chip technology, there is still a need to immobilize biomolecules (especially proteins) on a microfluidics apparatus, while maintaining high biological activity and electroosmotic flow (EOF) capability. This invention relates to the discovery that certain polymers containing both ionic and hydrophobic groups can be reproducibly adhered to microfluidic channels and can be used to simulataneously immobilize biocatalysts with good catalytic activity while supporting EOF.

Biocatalytic Solgel Microarrays

Chemicals affect living organisms in both positive and negative ways, depending on the chemical. Chemicals can have different effects on different organisms, for example, potential drugs that work in animals studies but fail in human trials. A major reason to these differences is that species, individuals, and organs all have different kinds and amounts of enzymes. There is a need for a technology to rapidly, effectively, and economically test the heatlh effects of chemicals.